Projects

• The aetiology and natural history of dementia in young adults.
• Risk factors in the development of early onset dementia.
• The clinical phenomenology of frontotemporal dementia versus Alzheimer's disease.
• Exploration of genetic factors in sporadic Alzheimer's disease and frontotemporal dementia.
• The epidemiology of early onset dementia in Western Australia.
• The epidemiology of Parkinson's disease in Geraldton and the Mid-West of Western Australia:
  • The interaction between the environment and Parkinson's disease
  • The Geraldton Midwest Parkinson's Disease project.
• New genes in familial frontotemporal dementia.
• The exploration of immunological genes in Alzheimer's disease and the dementias.
• The development of diagnostic tests, particularly functional molecular imaging such as PET scanning in the differentiation of dementia in young adults.
• Exploration of genetic factors and genomic analysis in subacute sclerosing panencephalitis, a cause of dementia in adolescents in countries with restricted immunisation, eg India.
• The ethics of the application of genetic Information to the diagnosis of dementing diseases.
• Genotype, phenotype correlations in Prion diseases (Creutzfeldt-Jakob disease).
• Juvenile Huntington's disease.
• Cognition in multiple sclerosis.
• Genotype/phenotype correlations in early onset dementia.
• Clinical and neuropathological correlations in early onset dementia.
• The structure and function of genes and proteins involved in dementing diseases.